MONAI before 1.6.0 is vulnerable to OS command injection in the nnUNetV2Runner component (monai.apps.nnunet.nnunetv2 runner). User-controlled values taken from the YAML configuration file (notably dataset name or id) and from CLI/kwargs arguments are concatenated into a command string without quoting or validation and then passed to subprocess with shell=True, so shell metacharacters (e.g., ';' on Linux, '&' on Windows) are interpreted. If a victim loads and processes a crafted configuration file — for example by instantiating nnUNetV2Runner with the malicious YAML and invoking a training/validation job such as train single model() — arbitrary commands are executed with the privileges of the user running the job.